Trapped in his own home, Jeff Daniels speaks about how his near-constant erection has cost him friends, destroyed his family life and ruined his acting career.
The Dumb and Dumber star, has 100 orgasms each day - but does not enjoy a single one.
Jeff Daniels is trapped in his own home by Persistent Genital Arousal Syndrome - which he developed in September 2012 when he slipped a disk in his back while getting out of a chair - and says his life is ruined by the condition.
The 60-year-old said: “Imagine being on your knees at your father's funeral beside his casket - saying goodbye to him and then you have nine orgasms right there, while your whole family is standing behind you.
“It makes you never want to have another orgasm for as long as you live.
“There's nothing pleasurable about it because even though it might feel physically good - you're completely disgusted by what's going on.”
He added: “If you're in public, if you're in front of kids - it's disgusting and it can break you real fast.
“It happened to me at the grocery store and when it was over there were around 150 people looking straight at me - why would I leave the house when something like this can happen.”
Jeff Daniels from Athens, Georgia has a wife and 3 kids who support him with napkins and toilet paper to clean up with.
While she does everything she can to support him his wife, Kathleen, is finding Jeff's condition just as hard to live with as he is.
She said: “We really struggle right now as he is unable to work and supply for his family and I feel like all the strain is on me.
“It's really upsetting, we don't do things that man and wife should do and we argue over things that should not be affecting us.”
“Because he sometimes has episodes at night we took the decision to sleep in separate beds. That can be very frustrating. You want the comfort from another person, particularly your husband but we don't have that.
“I really miss the old Jeff, we used to have a lot of fun and one day I pray that he will come back to me. Maybe the doctors will find a cure for this - I don't know - I just really hope that they do.”
“He struggles to be a good father to the children because they obviously don't understand what is happening,” added Kathleen. “He can't take them to practice - can't play ball with them, it's really hard.”
Despite suffering from a near constant erection Jeff and Kathleen rarely have sex. Jeff added: “Occasionally we will but it's very frustrating for both of us as this condition has left me unable to finish.
“I've tried reading about it, tried going to doctors but nobody can help me - I don't know what I'm going to do. I just want to get my old life back - I just want to get back what this condition has taken from me.”
Despite many medical professionals being unable to even diagnose the condition, there are some specialists in the field.
Dr Dena Harris is a gynecologist who has mainly worked with women who suffer with PGAS. Speaking from her office in New York, she said: “It's clear Jeff is really suffering and I'm sure there are some people who will say that this is just in his head.
“But it's not - it's a serious medical condition and I just hope he gets the help he so desperately needs. Being aroused can be a wonderful thing but this is not like arousal, it's not even sexual. It's a horrendous spasm and it can be terribly painful.
“Jeff looks like he is in pain - not just emotionally but physically as well. I've got to be honest, there is help available but if Jeff doesn't get help soon then there could be huge risks in the future.
“Suicide is always a concern when people suffer from this condition - they feel like they have no other way to escape it.”